Graham 1993.
Methods | RCT. Individual women. Multi‐centre. 2‐arm study. | |
Participants |
Inclusion criteria
Exclusion criteria
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Interventions |
Intervention: cephalosporin (B1).
Comparison: penicillin (A4).
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Outcomes | Genital tract cultures. | |
Notes |
Setting: University Medical Centre, Lubbock & LBJ General Hospital, Houston, Texas, US. Subgroups
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Risk of bias | ||
Bias | Authors' judgement | Support for judgement |
Random sequence generation (selection bias) | Low risk | "...computer‐generated number..." |
Allocation concealment (selection bias) | Unclear risk | No information provided. |
Blinding of participants and personnel (performance bias) All outcomes | High risk | Antibiotic administration was not blinded. |
Blinding of outcome assessment (detection bias) All outcomes | Unclear risk | Antibiotic administration was not blinded but outcome assessor could have been blinded. |
Incomplete outcome data (attrition bias) All outcomes | Low risk | No exclusions of women were reported. |
Selective reporting (reporting bias) | Unclear risk | We did not asses trial protocol. |
Other bias | Unclear risk | Baseline characteristics across groups not reported and other aspects of possible bias unclear. No information about funding source of study. |