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. 2014 Nov 17;2014(11):CD008726. doi: 10.1002/14651858.CD008726.pub2
Study Reason for exclusion
Andrews 2003 Study compared 2 different 2nd generation cephalosporins. Study will be considered in the review on 'Different regimens of cephalosporin antibiotic given to women routinely for preventing infection after caesarean section'.
Baheraie 1997 Compares single vs multiple doses of same class of antibiotic (cephalosporin). Study will be considered in the review ‘Different regimens of cephalosporin antibiotic given to women routinely for preventing infection after caesarean section’.
Beksac 1989 Quasi‐RCT ‐ "...randomly assigned according to the last number of her hospital notes..."
Berkeley 1990 Study compared a cephalosporin (cefotaxime) by 2 different routes of administration, IV and lavage.
Bernstein 1994 Study compared 2 different cephalosporins, cefotetan versus cefoxitin. Study will be considered in the review on 'Different regimens of cephalosporin antibiotic given to women routinely for preventing infection after caesarean section'.
Bilgin 1998 Quasi‐RCT, allocated women to groups according to last digit of hospital number.
Boothby 1984 Study compared a cephalosporin (cefoxitin) by 2 different routes of administration, IV and lavage.
Carlson 1990 Study compared 2 different cephalosporins, cefazolin versus cefotetan. Study will be considered in the review on 'Different regimens of cephalosporin antibiotic given to women routinely for preventing infection after caesarean section'.
Chamberlain 1993 Study compared ampicillins plus sulbactam versus ampicillin alone. Study will be considered in the review on 'Different regimens of penicillin antibiotic given to women routinely for preventing infection after caesarean section'.
Chittacharoen 1998 Study compared 2 different ampicillins (augmentin vs ampicillin). Study will be considered in the review on 'Different regimens of penicillin antibiotic given to women routinely for preventing infection after caesarean section'.
Conover 1984 Study compared a cephalosporin (cefoxitin) by 2 different routes of administration, IV and irrigation.
Crombleholme 1987 Study compared 2 versus 3 doses of a penicillin (mezlocillin). Study will be considered in review on 'Different regimens of penicillin antibiotic given to women routinely for preventing infection after caesarean section'.
Crombleholme 1989 Study compared 2 different 2nd generation cephalosporins. Study will be considered in the review on 'Different regimens of cephalosporin antibiotic given to women routinely for preventing infection after caesarean section'.
Cunningham 1983 Study compared 2 differing timings of giving the prophylactic antibiotics, before and after cord clamping.
D'Angelo 1980 Comparison of short‐ versus long‐course prophylactic antibiotic treatment. Authors do not list dose of drug at time of first administration, nor do they indicate the time of administration (pre‐operative, cord clamp). The authors are not even clear about the identity of the drug which begins the prophylactic regimen.
 They state that it is a random study but provide no details of mechanism.
De Palma 1980 At the start of the study 2 arms: 1 a no treatment arm, the other composed of women given either cefamandole or penicillin plus gentamicin. It would have been possible to try and dissect important information from the study except that they changed the antibiotic regimen after treating 57/105 women in the cefamandole subgroup.
 A co‐intervention (addition of chloramphenicol) was also applied to 3/105 women in the cefamandole subgroup and 4/104 women in the penicillin/gentamicin arm.
De Palma 1982 Timing of delivery of antibiotics for prophylaxis not specified. Authors state antibiotics given within 90 minutes of delivery with no indication as to whether these might have been given pre‐, post‐ or intra‐operatively. Mechanism of randomisation clearly inadequate.
Digumarthi 2008 Quasi‐RCT, allocated women to groups alternatively.
Ding 2000 Study compared 2 different cephalosporins from 1st and 2nd generations. Study will be considered in the review on 'Different regimens of cephalosporin antibiotic given to women routinely for preventing infection after caesarean section'.
Donnenfeld 1986 Study compared a cephalosporin (cefazolin) by 2 different routes of administration, IV and lavage.
Duff 1987 Study compared 2 different cephalosporins, cefazolin versus cefonicid; 1 g after cord clamped. Study will be considered in the review on 'Different regimens of cephalosporin antibiotic given to women routinely for preventing infection after caesarean section'.
Elliot 1982 Study compared a penicillin, ampicillin, given in differing multiple doses. Study will be considered in review on 'Different regimens of penicillin antibiotic given to women routinely for preventing infection after caesarean section'.
Elliot 1986 Study compared a cephalosporin, cefoxitin, given in different ways, IV or lavage, or a combination of IV plus lavage.
Fejgin 1993 This study compared 2 different cephalosporins from 2nd and 3rd generations. Study will be considered in the review on 'Different regimens of cephalosporin antibiotic given to women routinely for preventing infection after caesarean section'.
Flaherty 1983 Comparison of pharmacokinetics of cefoxitin when administered by intravenous versus intraperitoneal lavage. Outcome variable of interest: concentration of drug in decidua. No outcomes of interest in our review are listed or were collected (i.e. febrile morbidity, endometritis, etc).
Fugere 1983 Study compared 2 different cephalosporins, cefoxitin (2 g) versus cefazolin (1g). Study will be considered in the review on 'Different regimens of cephalosporin antibiotic given to women routinely for preventing infection after caesarean section'.
Galask 1988 Study compared 2 different cephalosporins, cefotetan (2 g, single dose, IV dose) versus cefoxitin (6 g, multiple doses (2 g each dose), IV); after cord clamped. Study will be considered in the review on 'Different regimens of cephalosporin antibiotic given to women routinely for preventing infection after caesarean section'.
Galask 1989 Study compared 2 different 2nd generation cephalosporins. Study will be considered in the review on 'Different regimens of cephalosporin antibiotic given to women routinely for preventing infection after caesarean section'.
Gall 1987 Study compared a penicillin, piperacillin (4 g, IV, after cord clamped) single dose versus multiple doses. Study will be considered in review on 'Different regimens of penicillin antibiotic given to women routinely for preventing infection after caesarean section'.
Gonen 1986 Study compared a cephalosporin, cefamandole, by 2 different routes of administration, lavage and multiple doses IV.
Gonik 1985 Study compared a cephalosporin, cefotaxime (IV, after cord clamped) single dose (1 g) versus multiple doses (3 x 1 g). Study will be considered in the review on 'Different regimens of cephalosporin antibiotic given to women routinely for preventing infection after caesarean section'.
Gonik 1994 Study compared 2 different 2nd generation cephalosporins. Study will be considered in the review on 'Different regimens of cephalosporin antibiotic given to women routinely for preventing infection after caesarean section'.
Gordon 1982 Study compared 2 different cephalosporins from 2nd and 3rd generations. Study will be considered in the review on 'Different regimens of cephalosporin antibiotic given to women routinely for preventing infection after caesarean section'.
Grujic 2009 Study not randomised, authors report that women weer allocated to groups according to the type of antibiotics prophylaxis administered as a single dose.
Gul 1999 Study compared different timings of the antibiotic prophylaxis (before versus after cord clamping).
Hager 1991 Study compared 3 cephalosporins, cefazolin (1 g) versus cefoxitin (2 g) versus cefotaxime (1 g); IV; after cord clamped. Study will be considered in the review on 'Different regimens of cephalosporin antibiotic given to women routinely for preventing infection after caesarean section'.
Hartert 1987 Study compared 2 cephalosporins, single dose cefonicid (1 g) versus multiple doses cefoxitin (2 g each); IV; after cord clamped. Study will be considered in the review on 'Different regimens of cephalosporin antibiotic given to women routinely for preventing infection after caesarean section'.
Hawrylyshyn 1983 Study compared a cephalosporin, cefoxitin, single dose (2 g) versus multiple dosed (2 g each); IV; after cord clamped. Study will be considered in the review on 'Different regimens of cephalosporin antibiotic given to women routinely for preventing infection after caesarean section'.
Ijarotimi 2012 Comparing the same antibiotics but using different time scales (24 hours vs 48 hours + oral for 5 days). Study may be considered for possible inclusion in another review.
Itskovitz 1979 Quasi‐RCT. Women were assigned to each of the 2 wings of the department according to the day of their admission.
Jakobi 1988 Study compared a cephalosporin, cefazolin, single dose (1 g) versus multiple doses (2 g each); IV; after cord clamped. Study will be considered in the review on 'Different regimens of cephalosporin antibiotic given to women routinely for preventing infection after caesarean section'.
Kreutner 1979 Study compared 2 cephalosporins, cephalothin versus cefamandole; 1 g; IV at differing times of administration. Study will be considered in the review on 'Different regimens of cephalosporin antibiotic given to women routinely for preventing infection after caesarean section'.
Lavery 1986 Study compared penicillin (mezlocillin) by differing routes of administration and single versus multiple doses. Study will be considered in review on 'Different regimens of penicillin antibiotic given to women routinely for preventing infection after caesarean section'.
Leonetti 1989 Study compared penicillin (piperacillin, IV after cord clamping) single (4 g) versus multiple doses (4 g each). Study will be considered in review on 'Different regimens of penicillin antibiotic given to women routinely for preventing infection after caesarean section'.
Leveno 1984 Study compared a cephalosporin (cefamandole 2 g) by 2 routes of administration, lavage versus IV.
Levin 1983 Study compared 2 different cephalosporins, cefoxitin versus cephapirin (2 g/L by irrigation). Study will be considered in the review on 'Different regimens of cephalosporin antibiotic given to women routinely for preventing infection after caesarean section'.
Luttkus 1997 Compares different doses of the same cephalosporin. Study will be considered in the review on ‘Different regimens of cephalosporin antibiotic given to women routinely for preventing infection after caesarean section (0732)’.
Lyimo 2012 Compares different doses of the same combination of antibiotics. Study may be considered for possible inclusion in another review.
Macones 2008 Study compared different timings of giving the prophylactic antibiotic.
Maggioni 1998 Study compared 2 different B‐lactams (F).
Major 1999 Study compared 2 different cephalosporins from 1st and 2nd generations. Study will be considered in the review on 'Different regimens of cephalosporin antibiotic given to women routinely for preventing infection after caesarean section'.
Mansani 1984 Study on antibiotics for women undergoing hysterectomy.
Masse 1988 Study compared a cephalosporin, cefoxitin (2 g IV after cord clamped) single dose versus multiple doses. Study will be considered in the review on 'Different regimens of cephalosporin antibiotic given to women routinely for preventing infection after caesarean section'.
Mathelier 1992 Study compared a cephalosporin, cefazolin, by different routes of administration, '2 g IV after cord clamped and saline irrigation of abdomen' versus '1 g IV after cord clamped and 1 g in 500 ml normal saline by irrigation'.
McGregor 1986 Study compared 2 cephalosporins, cefotetan (2 g IV after cord clamped) versus cefoxitin (2 g IV and 2 further doses at 4 and 8 hours post‐operatively).
McGregor 1988 Study compared 2 cephalosporins, cefotetan (2 g IV after cord clamped) versus cefoxitin (2 g IV and 2 further doses at 4 and 8 hours post‐operatively).
Meyer 2000 This study compared a cephalosporin versus the same cephalosporin plus another antibiotic. More specifically, cefazolin versus cefalozin‐metronidazole. So this study compared B1 versus B1 + I and will be considered in the review 'Different regimens of cephalosporin antibiotic given to women routinely for preventing infection after caesarean section'.
Meyer 2003 Study compared 2 different 1st generation cephalosporins 1 in combination with metronidazole versus the antibiotic alone.
Neuman 1990 Study comparing penicillin G (10 million units IV after cord clamped) plus tetracycline (250 mg IM after cord clamped) versus ampicillin (2 g) plus tetracycline (1.5 g per day, to complete 3 days). Study will be considered in review on 'Different regimens of penicillin antibiotic given to women routinely for preventing infection after caesarean section'.
O'Leary 1986 Study compared a penicillin (ampicillin 2 g IV intraoperatively and 7 further doses) versus the same penicillin regime plus another antibiotic (gentamicin 2 g IV after cord clamping and 6 further doses). So the study compared A4 versus A4 + G and will be considered in the review 'Different regimens of penicillin antibiotic given to women routinely for preventing infection after caesarean section'.
Ovalle 1996 Quasi‐RCT as “Patients were distributed strictly by order of admission in five groups:”.
Parsons 1985 Study compared 2 cephalosporins, cefonicid (1 g IV after cord clamped) versus cefoxitin (2 g IV after cord clamped and 4 additional doses). Study will be considered in the review on 'Different regimens of cephalosporin antibiotic given to women routinely for preventing infection after caesarean section'.
Patacchiola 2000 Study compared 2 3rd generation penicillins at differing doses. Study will be considered in the review on 'Different regimens of penicillin antibiotic given to women routinely for preventing infection after caesarean section'.
Periti 1988 Study compared 2 different cephalosporins from 1st and 2nd generations. Study will be considered in the review on 'Different regimens of cephalosporin antibiotic given to women routinely for preventing infection after caesarean section'.
Peterson 1990 Study compared 2 different cephalosporins by 2 different routes of administration. Cefazolin (2 g IV after cord clamped) versus cefamandole (2 g IV after cord clamped) versus cefazolin (2 g in 1 L in normal saline by lavage) versus cefamandole (2 g in 1 L normal saline by lavage). Study will be considered in the review on 'Different regimens of cephalosporin antibiotic given to women routinely for preventing infection after caesarean section'.
Pevzner 2009 Compares giving prophylactic antibiotics before or after cord clamping. Study will be considered for review on 'Timing of prophylactic antibiotics for preventing infectious morbidity in women undergoing caesarean section'.
Prasuna 2011 Quasi‐RCT, allocated women to groups alternately.
Puri 1991 Quasi‐RCT, allocated women to groups alternately.
Rayburn 1985 Study compared a 1st and 3rd generation cephalosporins. Study will be considered in the review on 'Different regimens of cephalosporin antibiotic given to women routinely for preventing infection after caesarean section'.
Rijhsinghani 1995 This study compares a single penicillin with a penicillin combination so should be considered for review ‘Different regimens of penicillin antibiotic given to women routinely for preventing infection after caesarean section’.
Rodriguez 1990 Study compared different timings of giving prophylactic antibiotics.
Roex 1987 Study compared a cephalosporin, cefoxitin (2 g IV after cord clamped) single dose versus multiple doses. Study will be considered in the review on 'Different regimens of cephalosporin antibiotic given to women routinely for preventing infection after caesarean section'.
Roy 2003 Study looked at women with acute pelvic infections.
Saravolatz 1985 Study compared cephalosporin (ceforanide) by 2 routes of administration, 2 g IV after cord clamped versus 2 g in 1 L normal saline by irrigation.
Scarpignato 1982 Study compared a cephalosporin (cefuroxime) by different length of administration, 750 mg IM 30 to 60 minutes pre‐operatively and again post‐operatively at 8 and 16 hours versus 750 mg IM to complete 5 days of therapy, first dose post‐operatively after return of woman to the ward.
Seton 1996 Study looked at different timings of giving 3rd generation cephalosporins.
Shakya 2010 Stuudy is unclear how women were allocated to groups and also compared single dose (Cefazolin + Metronidazole) vs multiple doses antibiotics
Stiver 1983 Study compared a cephalosporin (cefoxitin) at different doses, 1 g IV after cord clamped versus 2 g IV after cord clamped. Study will be considered in the review on 'Different regimens of cephalosporin antibiotic given to women routinely for preventing infection after caesarean section'.
Stiver 1984 Study compared 2 different cephalosporins from 1st and 2nd generations. Study will be considered in the review on 'Different regimens of cephalosporin antibiotic given to women routinely for preventing infection after caesarean section'.
Sullivan 2006 Study looked at different timings of giving 1st generation cephalosporins for prophylaxis. Study will be considered in the review on 'Different regimens of cephalosporin antibiotic given to women routinely for preventing infection after caesarean section'.
Sullivan 2007 Study looked at different timings of giving 1st generation cephalosporins for prophylaxis.
Tassi 1987 Study compared a cephalosporin (ceftazidime) by single (2 g IM 1 hour pre‐operative) versus multiple doses (2 g IM 1 hour pre‐operative plus 2 additional doses). Study will be considered in the review on 'Different regimens of cephalosporin antibiotic given to women routinely for preventing infection after caesarean section'.
Teansutikul 1993 Study compared different doses of ampicillins. Study will be considered in the review on 'Different regimens of penicillin antibiotic given to women routinely for preventing infection after caesarean section'.
Thigpen 2005 Study looked at different timings of giving 1st generation cephalosporins for prophylaxis.
van Beekhuizen 2008 Study looked at single dose of ampicillin plus metronidazole versus multiple doses in low‐income setting.
van Velzen 2009 Study compared a single dose of ampicillin + metronidazole versus multiple doses.
Varner 1986 Study compared a cephalosporin (cefotetan) by single (2 g IV after cord clamping) versus multiple doses (2 g IV after cord clamping plus 2 additional doses). Study will be considered in the review on 'Different regimens of cephalosporin antibiotic given to women routinely for preventing infection after caesarean section'.
von Mandach 1993 Study compared 2 cephalosporins, ceftriaxone 1 g IV after cord clamped versus cefoxitin 1 g IV after cord clamped and 2 additional doses at 8 and 16 hours after first dose. Study will be considered in the review on 'Different regimens of cephalosporin antibiotic given to women routinely for preventing infection after caesarean section'.
Wagner 2006 Study compared 2 different 3rd generation cephalosporins. Study will be considered in the review on 'Different regimens of cephalosporin antibiotic given to women routinely for preventing infection after caesarean section'.
Warnecke 1982 Study compares prophylactic antibiotics with what we presume is 'no treatment' as the English summary only refers to the ‘control group’. Study will be considered for review on 'Antibiotic prophylaxis versus no prophylaxis for preventing infection after cesarean section'.
Watts 1991 Study looked at upper genital isolates at birth as predictors of infection.
Wax 1997 Study looked at different timings of cephalosporin administration (before and after cord clamping).
Wu 1991 Study compared a penicillin versus the same penicillin plus another antibiotic. More specifically, ampicillin versus ampicillin‐gentamicin. So the study compared A4 versus A4 + G and will be considered in the review on 'Different regimens of penicillin antibiotic given to women routinely for preventing infection after caesarean section'.
Xu 1997 Study looked at cephalosporins versus penicillins but the penicillins were sometimes given with other classes of antibiotics and the data could not be separated.
Yildirim 2009 Study compares administration of antibiotics before and after cord clamping. Study will be considered for review on ‘Different regimens of cephalosporin antibiotic given to women routinely for preventing infection after caesarean section.
Zutshi 2008 Compared different dosage regimens of the same antibiotic, but the specific antibiotic is not given in this conference abstract.

IM: intramuscular
 IV: intravenous
 RCT: randomised controlled trial
 vs: versus