2. rTMS parameters of included trials.
Study | Duration | Stimulator and Coil | rTMS placement | rTMS frequency | Intensity % motor threshold | Medications |
Di Lazarro 2006 | Five consecutive days per month for six months | MagPro stimulator and fig 8 coil | Motor cortex of both hemispheres | 50 Hz | 80% of action motor threshold | All participants were taking riluzole |
Di Lazarro 2009 | Five consecutive days per month for 12 months | MagPro stimulator and fig 8 coil | Motor cortex of both hemispheres | 50 Hz | 80% of action motor threshold | All participants were taking riluzole |
Zanette 2008 | Five consecutive days per week for two weeks | Super Rapid magnetic stimulator and fig 8 coil | Motor cortex of thenar muscles and tibialis anterior muscles were stimulated separately on both hemispheres | 5 Hz | 110% of resting motor threshold | All participants were taking riluzole |
rTMS: repetitive transcranial magnetic stimulation