| Methods |
Randomised, open, cross‐over study |
| Participants |
7 participants with McArdle disease (6 men, 1 woman), mean age 38 ± 5 years (range 25 to 60 years) |
| Interventions |
Fixed menu plan with recipes for 3 days
Carbohydrate‐rich diet versus protein‐rich diet |
| Outcomes |
Incremental cycle test 2/3 max for 15 minutes then max to exhaustion |
| Notes |
|
| Risk of bias |
| Bias |
Authors' judgement |
Support for judgement |
| Random sequence generation (selection bias) |
High risk |
Participants were alternately allocated to a carbohydrate‐rich or protein‐rich diet for the first arm of the study |
| Allocation concealment (selection bias) |
High risk |
Investigators enrolled participants according to the sequential order of inclusion |
| Blinding (performance bias and detection bias)
All outcomes |
High risk |
No participant or observer blinding |
| Incomplete outcome data (attrition bias)
All outcomes |
Low risk |
No dropouts or missing data |
| Selective reporting (reporting bias) |
Low risk |
Results were reported equally for both groups |
| Other bias |
High risk |
Participants were asked to follow recipes and weigh and record food on a form. There was no direct observation and food was not pre‐prepared for the participants |
