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. 2014 Nov 12;2014(11):CD003458. doi: 10.1002/14651858.CD003458.pub5

Kushner 1990.

Methods Open, controlled study
Participants 3 adults (age and sex not specified)
 3 controls (age, sex, height and weight matched)
Interventions Baseline assessments were performed after fasting, 100 g of oral dextrose or 0.33 mg/kg branched‐chain amino acids. Participants were assessed after 1 and 2 months of 0.3 g/kg of dietary branched‐chain amino acids as a supplement to their habitual diet
Outcomes Maximal concentric strength or torque at 60 cycles per minute and muscle endurance measured as absolute work performed to fatigue (60 or 90 cycles per minute with a 2 minute rest between sets)
Notes  
Risk of bias
Bias Authors' judgement Support for judgement
Random sequence generation (selection bias) High risk The method of sequence generation was not described
Allocation concealment (selection bias) High risk There was no allocation concealment
Blinding (performance bias and detection bias) 
 All outcomes High risk There was no participant or observer blinding
Incomplete outcome data (attrition bias) 
 All outcomes Low risk Data were complete for each intervention
Selective reporting (reporting bias) Low risk Data from each intervention were equally reported; outcomes were reported as specified in methods
Other bias Low risk No other source of bias identified