1 Leaving the study early: 1. Any reason |
1 |
|
Risk Ratio (M‐H, Random, 95% CI) |
Subtotals only |
1.1 short term |
1 |
198 |
Risk Ratio (M‐H, Random, 95% CI) |
1.33 [0.67, 2.67] |
2 Leaving the study early: 2. Due to adverse events |
1 |
|
Risk Ratio (M‐H, Random, 95% CI) |
Subtotals only |
2.1 short term |
1 |
198 |
Risk Ratio (M‐H, Random, 95% CI) |
1.33 [0.67, 2.67] |
3 Global state: 1. Change over time ‐ no better or deterioration (ITT) |
1 |
|
Risk Ratio (M‐H, Random, 95% CI) |
Subtotals only |
3.1 short term |
1 |
198 |
Risk Ratio (M‐H, Random, 95% CI) |
1.11 [0.79, 1.55] |
4 Adverse events: Movement disorders |
1 |
|
Risk Ratio (M‐H, Random, 95% CI) |
Subtotals only |
4.1 akathisia ‐ short term |
1 |
198 |
Risk Ratio (M‐H, Random, 95% CI) |
0.85 [0.56, 1.29] |
4.2 dyskinesia ‐ short term |
1 |
198 |
Risk Ratio (M‐H, Random, 95% CI) |
0.36 [0.13, 0.95] |
4.3 dystonia ‐ short term |
1 |
198 |
Risk Ratio (M‐H, Random, 95% CI) |
0.33 [0.01, 8.08] |
4.4 parkinsonism ‐ short term |
1 |
198 |
Risk Ratio (M‐H, Random, 95% CI) |
1.21 [0.84, 1.73] |
5 Other adverse events: 1. Anticholinergic |
1 |
|
Risk Ratio (M‐H, Random, 95% CI) |
Subtotals only |
5.1 blurred vision ‐ short term |
1 |
198 |
Risk Ratio (M‐H, Random, 95% CI) |
3.0 [0.12, 72.76] |
6 Other adverse events: 2. Arousal |
1 |
|
Risk Ratio (M‐H, Random, 95% CI) |
Subtotals only |
6.1 drowsiness ‐ short term |
1 |
198 |
Risk Ratio (M‐H, Random, 95% CI) |
1.43 [0.57, 3.60] |
6.2 excitation ‐ short term |
1 |
198 |
Risk Ratio (M‐H, Random, 95% CI) |
4.75 [1.68, 13.46] |
6.3 insomnia ‐ short term |
1 |
198 |
Risk Ratio (M‐H, Random, 95% CI) |
1.31 [0.94, 1.82] |
7 Other adverse events: 3. At least one |
1 |
|
Risk Ratio (M‐H, Random, 95% CI) |
Subtotals only |
7.1 short term |
1 |
198 |
Risk Ratio (M‐H, Random, 95% CI) |
1.01 [0.89, 1.16] |
8 Other adverse events: 4. Cardiovascular |
1 |
|
Risk Ratio (M‐H, Random, 95% CI) |
Subtotals only |
8.1 faintness, dizziness, weakness ‐ short term |
1 |
198 |
Risk Ratio (M‐H, Random, 95% CI) |
1.5 [0.71, 3.18] |
8.2 lassitude ‐ short term |
1 |
198 |
Risk Ratio (M‐H, Random, 95% CI) |
1.07 [0.55, 2.10] |
9 Other adverse events: 5. Central nervous system |
1 |
|
Risk Ratio (M‐H, Random, 95% CI) |
Subtotals only |
9.1 confusion ‐ short term |
1 |
198 |
Risk Ratio (M‐H, Random, 95% CI) |
0.67 [0.11, 3.90] |
9.2 disturbance of consciousness ‐ short term |
1 |
198 |
Risk Ratio (M‐H, Random, 95% CI) |
1.0 [0.06, 15.76] |
9.3 dysarticulation ‐ short term |
1 |
198 |
Risk Ratio (M‐H, Random, 95% CI) |
0.83 [0.38, 1.84] |
9.4 headache ‐ short term |
1 |
198 |
Risk Ratio (M‐H, Random, 95% CI) |
0.33 [0.09, 1.19] |
9.5 seizure ‐ short term |
1 |
198 |
Risk Ratio (M‐H, Random, 95% CI) |
0.0 [0.0, 0.0] |