Suprapto 2002.
Methods | Quasi‐RCT. A double‐blind, placebo, controlled trial. | |
Participants | Inclusion criteria:
Exclusion criteria:
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Interventions | Intervention group 1: 22 women; group IFR received iron‐folate tablets + 5 mg riboflavin 7 days a week for 60 days. Intervention group 2: 29 women; group IFA received iron‐folate tablets + 2.75 mg retinyl palmitate (equal to 5000 IU vitamin A) 7 days a week for 60 days. Intervention group 3: 23 women; group IFRA received iron‐folate tablets + 5 mg riboflavin + 2.75 mg retinyl palmitate 7 days a week for 60 days. Control group: 29 women; group IF received iron‐folate tablets + 5 mg glucose 7 days a week for 60 days. |
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Outcomes | Maternal levels of vitamin A and riboflavin. | |
Notes | Vitamin A levels were measured before starting supplementation. Country: Indonesia. Study setting: health centre ANC. |
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Risk of bias | ||
Bias | Authors' judgement | Support for judgement |
Random sequence generation (selection bias) | High risk | "allocated alternately." |
Allocation concealment (selection bias) | High risk | "allocated alternately." |
Blinding of participants and personnel (performance bias) All outcomes | Low risk | "participants and personnel double‐blind." |
Blinding of outcome assessment (detection bias) All outcomes | Unclear risk | Information not given. |
Incomplete outcome data (attrition bias) All outcomes | Low risk | 19 (18.4%) were excluded from the analyses: 9 premature labour, 1 stillbirth, 1 migration, 1 refusal to give blood, 2 nausea and vomiting and 5 incorrect dates given for last menstruation but with normal deliveries. |
Selective reporting (reporting bias) | Unclear risk | The protocol of the study is not available at the moment. |
Other bias | High risk | Women in group IFRA were shorter and lighter than those in other groups. |