1. Overview of treatment characteristics of the included herniorrhaphy studies.
Antibiotic | Dose (g) | Administration route | Follow‐up period | Operative time (minutes); (mean ± SD or median (range)) | Infection risk environment (Infection percentage in control group) |
Remark | |
Andersen 1980 | AMP | 1 | in fascia | 1 m, 3 m, 6 m, 12 m | not reported | Low (4.0%) | Several surgery types performed |
Evans 1973 | CLR | 1 (3×) | intravenous (1x)/ intramuscular (2x) | 1 m | not reported | Low (4.1%) | Several surgery types performed |
Lazorthes 1992 | CAM | 0.75 | subcutaneous (added to local anaesthesia) | 1 m | not reported | Low (4.6%) | |
Platt 1990 | CON | 1 | intravenous | 1 w, 4 to 6 w | PG: 75 ± 32 / CG: 75 ± 30 | Low (1.9%) | Several surgery types performed |
Taylor 1997 | AMC | 1.2 | intravenous | 4 to 6 w | not reported | High (8.9%) |
PG = prophylactic group, CG = control group
AMC = Amoxicillin‐clavoulanic acid, AMP = ampicillin, CAM = cefamandole, CON = cefonicid, CLR = cephaloridine (Abbreviations according to EUCAST System for Antimicrobial Abbreviations)
w = week, m = month, y = year
Infection risk environment (L = low; ≤ 5% infections in control group for all wound infections (SSSI + DSSI), H = high; > 5% infections in control group for all wound infections (SSSI + DSSI) ).