1	(Randomized controlled trial/ not ((exp experimental organism/ or animal tissue/ or animal cell/ or exp animal disease/ or exp carnivore disease/ or exp bird/ or exp experimental animal welfare/ or exp animal husbandry/ or animal behavior/ or exp animal cell culture/ or exp mammalian disease/ or exp mammal/ or exp marine species/ or nonhuman/ or animal.hw.) not human/)) or ((((((((((((Controlled clinical study/ or Random$.ti,ab. or randomization/ or intermethod comparison/ or placebo.ti,ab. or (compare or compared or comparison).ti. or ((evaluated or evaluate or evaluating or assessed or assess) and (compare or compared or comparing or comparison)).ab. or (open adj label).ti,ab. or ((double or single or doubly or singly) adj (blind or blinded or blindly)).ti,ab. or double blind procedure/ or parallel group$1.ti,ab. or (crossover or cross over).ti,ab. or ((assign$ or match or matched or allocation) adj5 (alternate or group$1 or intervention$1 or patient$1 or subject$1 or participant$1)).ti,ab. or (assigned or allocated).ti,ab. or (controlled adj7 (study or design or trial)).ti,ab. or (volunteer or volunteers).ti,ab. or human experiment/ or trial.ti.) not Randomized controlled trial/ not (random$ adj sampl$ adj7 ("cross section$" or questionnaire$1 or survey$ or database$1)).ti,ab. not (comparative study/ or controlled study/ or randomi?ed controlled.ti,ab. or randomly assigned.ti,ab.)) or Cross‐sectional study/) not (randomized controlled trial/ or controlled clinical study/ or controlled study/ or randomi?ed controlled.ti,ab. or control group$1.ti,ab.)) or (((case adj control$) and random$) not randomi?ed controlled).ti,ab. or (Systematic review not (trial or study)).ti. or (nonrandom$ not random$).ti,ab. or "Random field$".ti,ab. or (random cluster adj3 sampl$).ti,ab. or (review.ab. and review.pt.)) not trial.ti.) or "we searched".ab.) and (review.ti. or review.pt.)) or "update review".ab. or (databases adj4 searched).ab. or (rat or rats or mouse or mice or swine or porcine or murine or sheep or lambs or pigs or piglets or rabbit or rabbits or cat or cats or dog or dogs or cattle or bovine or monkey or monkeys or trout or marmoset$1).ti.) and animal experiment/) or Animal experiment/) not (human experiment/ or human/))	2448495
2	exp 'inguinal hernia'/ or exp 'femoral hernia'/ or ((inguin* or groin* or bladder or femoral or crural) adj7 herni*).ti,ab,hw. or femorocele.ti,ab,hw. or lichtenstein.ti,ab,hw. or bassini.ti,ab,hw. or shouldice.ti,ab,hw.	23865
3	exp 'antibiotic agent'/ or exp 'antibiotic prophylaxis'/ or antibiotic*.ti,ab,hw. or ((antibacterial or 'anti bacterial') adj (compound* or agent*)).ti,ab,hw. or prophylaxis.ti,ab,hw. or 'anti microb*'.ti,ab,hw. or antimicrob*.ti,ab,hw. or antiinfecti*.ti,ab,hw. or 'anti infecti*'.ti,ab,hw.	1755258
4	2 and 3	1186
5	1 and 4	83
6	(elsevier or canadian or embase).cr.	24995844
7	5 and 6	74