Suknaic 2008.

Methods	RCT n=50
Participants	CAF adults and children
Interventions	Botox 10u vs LIS
Outcomes	Healing Minor incontinence
Notes	AS inadequate, AC no, B no, SS not stated R ‐ no (first 30 patients in one arm, second 30 in second arm) ITT+ Drop‐outs 10 Follow‐up 6 months
Risk of bias
Bias	Authors' judgement	Support for judgement
Random sequence generation (selection bias)	High risk	Inadequate randomisation process.
Allocation concealment (selection bias)	High risk	not concealed
Blinding (performance bias and detection bias) All outcomes	High risk	Not blinded due to injection vs surgery
Selective reporting (reporting bias)	Low risk	appropriate outcomes/side effects reported
Other bias	High risk	>10% drop outs,
Duration of Follow‐up 6 months or more	Low risk	6 months