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. 2012 Feb 15;2012(2):CD003431. doi: 10.1002/14651858.CD003431.pub3

Tankova 2002.

Methods RCT n=19
Participants CAF
Interventions Isosorbide mononitrate 
 bid 3 wk.s 
 n = 19
Outcomes healing, headache
Notes 3 mo f/u 
 AS,AC,B,SS no 
 0 drop outs
Risk of bias
Bias Authors' judgement Support for judgement
Random sequence generation (selection bias) Unclear risk not stated
Allocation concealment (selection bias) Unclear risk D ‐ Not used
Selective reporting (reporting bias) Low risk appropriate outcomes/side effects reported
Other bias Low risk 0 drop outs,
Duration of Follow‐up 6 months or more High risk 3 months