| Methods |
RCT n=35 |
| Participants |
CAF & AAF |
| Interventions |
GTN 0.2% tid vs Xylocaine |
| Outcomes |
Healing
Pain Relief
ARM
Headache |
| Notes |
R?OK
ITT ‐ |
| Risk of bias |
| Bias |
Authors' judgement |
Support for judgement |
| Random sequence generation (selection bias) |
Unclear risk |
R?OK |
| Allocation concealment (selection bias) |
Low risk |
A ‐ Adequate |
| Blinding (performance bias and detection bias)
All outcomes |
Low risk |
|
| Selective reporting (reporting bias) |
Low risk |
appropriate outcomes/side effects reported |
| Other bias |
Low risk |
ITT |
| Blinding of participants and personnel (performance bias)
All outcomes |
Low risk |
|
| Blinding of outcome assessment (detection bias)
All outcomes |
Low risk |
|
| Duration of Follow‐up 6 months or more |
High risk |
4 weeks |
