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. 2012 Feb 15;2012(2):CD003431. doi: 10.1002/14651858.CD003431.pub3

Boschetto 2004.

Methods RCT n=36
Participants CAF
Interventions GTN 0.2% vs. hydrodynamic dilator x 1 
 n=36
Outcomes healing, pain relief, headache, AI
Notes 2 y f/u, 
 AS,AC, B, SS n.s. 
 Exc. n.s. 
 0 drop outs
Risk of bias
Bias Authors' judgement Support for judgement
Random sequence generation (selection bias) Unclear risk not specified
Allocation concealment (selection bias) Unclear risk D ‐ Not used
Blinding (performance bias and detection bias) 
 All outcomes Unclear risk not specified
Selective reporting (reporting bias) Low risk appropriate outcomes/side effects reported
Other bias Low risk 0 drop outs
Duration of Follow‐up 6 months or more Low risk 24 months