| Methods |
RCT n=30 |
| Participants |
CAF |
| Interventions |
GTN 0.2% o. vs. Botox 20 u
n=30 |
| Outcomes |
healing
recurrence
headache |
| Notes |
36 mo. follow‐up (f/u).
Allocation sequence (AS), allocation concealment (AC), Blinding (B) and sample size (SS) not stated.
0 drop outs |
| Risk of bias |
| Bias |
Authors' judgement |
Support for judgement |
| Random sequence generation (selection bias) |
Unclear risk |
not stated |
| Allocation concealment (selection bias) |
Unclear risk |
D ‐ Not used |
| Blinding (performance bias and detection bias)
All outcomes |
Unclear risk |
not stated |
| Selective reporting (reporting bias) |
Low risk |
appropriate outcomes/side effects reported |
| Other bias |
Low risk |
0 drop outs, |
| Duration of Follow‐up 6 months or more |
Low risk |
36 months follow up |
