| Methods |
RCT n=32 |
| Participants |
CAF |
| Interventions |
GTN 0.25%, cryothermal dilator to 27mm and both
n=48 |
| Outcomes |
healing, recurrence |
| Notes |
2 year f/u
ASok,ACns, B ok, SS no.
1 DO @ for GTN alone and CTD |
| Risk of bias |
| Bias |
Authors' judgement |
Support for judgement |
| Random sequence generation (selection bias) |
Low risk |
OK |
| Allocation concealment (selection bias) |
Unclear risk |
D ‐ Not used |
| Blinding (performance bias and detection bias)
All outcomes |
Low risk |
OK |
| Selective reporting (reporting bias) |
High risk |
SEs not reported |
| Duration of Follow‐up 6 months or more |
High risk |
6 weeks |
