| Methods |
RCT n=52 |
| Participants |
CAF |
| Interventions |
GTN 0.2% vs. nifedipine 0.2%
n=52 =
variable duration up to 24 w (m = 11.7 w |
| Outcomes |
healing, recurrence, headache, pain relief |
| Notes |
variable f/u m 8 and 7 mo
AS,AC, B SS ok
8 drop outs, 7 from Nif. |
| Risk of bias |
| Bias |
Authors' judgement |
Support for judgement |
| Random sequence generation (selection bias) |
Low risk |
OK |
| Allocation concealment (selection bias) |
Unclear risk |
D ‐ Not used |
| Blinding (performance bias and detection bias)
All outcomes |
Low risk |
OK |
| Selective reporting (reporting bias) |
Low risk |
appropriate outcomes/side effects reported |
| Other bias |
High risk |
>10% drop outs, variable follow ups |
| Duration of Follow‐up 6 months or more |
High risk |
12‐18 weeks |
