Jones 2006.

Methods	RCT n=30
Participants	CAF Adults
Interventions	Botox 25u + GTN 0.2% bid 8 weeks vs Botox 25u
Outcomes	Healing Incontinence
Notes	AS adequate, AC adequate, B yes, SS stated but not achieved ITT+ ROK 0 drop outs F/U 8 weeks
Risk of bias
Bias	Authors' judgement	Support for judgement
Random sequence generation (selection bias)	Low risk	ROK
Allocation concealment (selection bias)	Low risk	Adequate randomisation
Blinding (performance bias and detection bias) All outcomes	Low risk	outcome assessor blinded
Selective reporting (reporting bias)	Low risk	appropriate outcomes/side effects reported
Other bias	Low risk	ITT+, 0 drop outs,
Duration of Follow‐up 6 months or more	High risk	8 weeks