| Methods |
RCT n=60 |
| Participants |
CAF |
| Interventions |
GTN 0.2% bid vs. diltiazem 2% bid 6 weeks |
| Outcomes |
Healing
Pain relief
recurrence
Headache |
| Notes |
ROK
ITT + |
| Risk of bias |
| Bias |
Authors' judgement |
Support for judgement |
| Random sequence generation (selection bias) |
Low risk |
ROK |
| Allocation concealment (selection bias) |
Low risk |
A ‐ Adequate |
| Blinding (performance bias and detection bias)
All outcomes |
Low risk |
|
| Selective reporting (reporting bias) |
Low risk |
appropriate outcomes/side effects reported |
| Other bias |
Low risk |
ITT+ |
| Blinding of participants and personnel (performance bias)
All outcomes |
Low risk |
|
| Blinding of outcome assessment (detection bias)
All outcomes |
Low risk |
|
| Duration of Follow‐up 6 months or more |
High risk |
12 weeks |
