Barrios 2009.

Methods	RCT; block randomisation
Participants	Medial tibiofemoral OA: n = 66 Male/female: 29/37 Mean age (years): 62 Mean BMI (kg/m2): 33 Grade of OA according to Kellgren & Lawrence: II = 27, III = 24, IV = 15
Interventions	I = full‐length (9º) wedged insole into shoe (n = 35) vs C = non‐custom neutral insole into shoe (n = 31) Follow‐up: 12 months
Outcomes	WOMAC, 6‐minute walking test, stair negotiation test
Notes	Mean and P values are presented, but SD values are missing
Risk of bias
Bias	Authors' judgement	Support for judgement
Random sequence generation (selection bias)	Low risk	Quote: "a block‐randomization was performed based on OA grade, gender, and age (greater or less than 55 years)"
Allocation concealment (selection bias)	Low risk	Quote: "the allocation was done by an administrative assistant unaware of the methodologies used"
Blinding (performance bias and detection bias) All outcomes	Low risk	Quote: "the subjects were blinded from group assignment"
Blinding of participants and personnel (performance bias) All outcomes	High risk	Participants assigned to the treatment group were tested to determine the amount of wedging Quote: "subjects who had no pain relieve (after wedging) were excluded from the study"
Blinding of outcome assessment (detection bias) All outcomes	Unclear risk	Blinding of assessors was not mentioned
Incomplete outcome data (attrition bias) All outcomes	Low risk	Intention‐to‐treat
Selective reporting (reporting bias)	High risk	Quote: "subjects who had no pain relieve (after wedging) were excluded from the study"