Bennell 2011.

Methods	RCT; computer‐generated block randomisation
Participants	Painful medial knee osteoarthritis: n = 200 Male/ female: 82/118 Mean age (years): 64 Mean BMI (kg/m2): 29.2 Mean varus (degrees): 181 Grade of medial OA according to Kellgren & Lawrence: II = 95, III = 105
Interventions	I = full‐length (5º) wedged insole into shoe (n = 103) vs C = neutral insole into shoe (n = 97) Follow‐up: 12 months
Outcomes	NRS scale (pain), WOMAC scale, physical activity scale for the elderly, average number of steps taken per day
Notes	No competing interests
Risk of bias
Bias	Authors' judgement	Support for judgement
Random sequence generation (selection bias)	Low risk	Quote: "Participants were stratified by disease severity (Kellgren and Lawrence grades 2 and 3) and sex and randomly allocated in permuted blocks of 6 to 12"
Allocation concealment (selection bias)	Low risk	Quote: "An independent investigator used a computer program to generate the randomisation sequence a priori. Allocation was sealed in opaque and consecutively numbered envelopes held centrally. Envelopes were opened sequentially by an independent person"
Blinding (performance bias and detection bias) All outcomes	Low risk	Quote: "a double blind randomised controlled trial"
Blinding of participants and personnel (performance bias) All outcomes	Low risk	Quote: "Participants were informed that two types of insoles were being compared but the insoles and study hypotheses were not described"
Blinding of outcome assessment (detection bias) All outcomes	Low risk	Quote: "A blinded examiner assessed the participants at baseline and 12 months" according to patient‐reported outcome measures; participants were blinded as well
Incomplete outcome data (attrition bias) All outcomes	Low risk	Intention‐to‐treat
Selective reporting (reporting bias)	Low risk	Complete data were reported