Comparison 1. Single gloves versus double gloves ‐ innermost.

Outcome or subgroup title	No. of studies	No. of participants	Statistical method	Effect size
1 Number of perforations in innermost gloves	14	8885	Odds Ratio (M‐H, Fixed, 95% CI)	4.10 [3.30, 5.09]
1.1 Single gloves versus standard double gloves	10	6163	Odds Ratio (M‐H, Fixed, 95% CI)	4.14 [3.26, 5.26]
1.2 Single gloves versus indicator systems	2	1532	Odds Ratio (M‐H, Fixed, 95% CI)	9.42 [4.18, 21.23]
1.3 Single gloves versus standard double gloves and indicator systems combined	1	508	Odds Ratio (M‐H, Fixed, 95% CI)	2.87 [0.12, 70.85]
1.4 Single orthopaedic gloves versus standard double gloves	1	682	Odds Ratio (M‐H, Fixed, 95% CI)	0.98 [0.43, 2.22]