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. 2020 Apr 21;15(4):e0231555. doi: 10.1371/journal.pone.0231555

Fig 1. The plasma activity of DPP4, FAP, PRCP and PREP in septic shock patients and ICU controls.

Fig 1

The plasma activity of DPP4 (A), FAP (B), PRCP (C) and PREP (D), expressed in U/L (median with interquartile range) on days 1, 3, 5 and 7 of the septic shock patients (n = 40) and in the ICU control group (n = 22). Differences between the control group and the different days in the patients were tested using linear mixed models, followed by a post-hoc analysis with Dunnett’s correction. Within the septic shock patients, pairwise differences between the days were modeled using linear mixed models, followed by a post-hoc Tukey’s correction. For PREP, the test was carried out on the log-transformed enzyme activity due to the non-normality of the residuals. * p ≤ 0.05; ** p ≤ 0.01; *** p ≤ 0.001. See also S2 Table. Abbreviations used: DPP4: dipeptidyl peptidase 4; FAP: fibroblast activation protein α; PRCP: prolylcarboxypeptidase; PREP: prolyl oligopeptidase; U/L: units per liter.