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. 2020 Apr 17;13:137–144. doi: 10.2147/JAA.S205709

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© 2020 Belbézier et al.

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Schematic diagram of biochemical pathways responsible for angioedema. Part I: Mast cell angioedema. (A) Mast cell activation by different modes (allergic or non-allergic). (B) Release of various mediators responsible for angioedema. Part II: Bradykinin angioedema (kallikrein-kinin system).

Abbreviations: C1-inh, C1inhibitor; ACE, angiotensin-converting enzyme.