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. 2020 Apr 17;13:3247–3257. doi: 10.2147/OTT.S242715

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© 2020 Li et al.

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Silencing of miR-148b eliminated the anti-tumor effect of si-LINC00346 on CRC cells. (A) The expression of miR-148b in HCT116 cells was detected by qRT-PCR (N = 3); (B) the OD₄₅₀ value of HCT116 cells was detected by CCK-8 assay (N = 3); (C) the apoptosis of HCT116 cells was detected by flow cytometry (N = 3). (D) The relative migrated rate in HCT116 cells was detected by wound healing assay (N = 3). (E) The relative number of invasive cells inHCT116 cells was detected by transwell assay (N = 3). *P < 0.05, **P < 0.01, ***P < 0.001 vs BLANK, si-NC+miR-NC or miR-NC; ^#P < 0.05, ^##P < 0.01 vs si-LINC00346 + miR-NC. N represented biological replicates. All experiments were repeated three times.