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. Author manuscript; available in PMC: 2020 Apr 21.
Published in final edited form as: Neuroscience. 2017 Aug 18;361:167–178. doi: 10.1016/j.neuroscience.2017.08.016

Table 1.

Distribution of CRFR1-GFP-ir cells in the developing mouse forebrain. Density and intensity of CRFR1-GFP-ir was rated visually during developmental periods P0, P4, and P21, as having −, No label; +/−, minimal but still noticeable labeling intensity/density of cells; +, low labeling intensity/density of cells; ++, moderate labeling intensity/cell density; +++, high labeling intensity/cell density; ++++, very high labeling intensity/cell density

P0 P4 P21
Brain region Male Female Male Female Male Female
Outer cortical layers + + ++ +++ +++ ++ ++
Middle cortical layers + + ++ ++ ++ ++++ ++++
Inner cortical layers + + +++ +++ ++ ++
Medial septum + + ++ ++ ++ ++
Lateral septum + + ++ ++ + +
Diagonal band + + ++ ++ ++ ++
Bed Nucleus of the Stria Terminalis, principal nucleus +++ +++ +++ +++ ++ ++
Lateral amygdaloid nucleus +/− +/− + + + +
Basolateral amygdaloid nucleus + + + + + +
Basomedial amygdaloid nucleus +++ +++ +++ +++ +++ +++
Central amygdaloid nucleus ++ ++ ++ ++ ++ ++
Medial amygdaloid nucleus +/− +/− + + + + + +
Cortical amygdaloid nucleus ++ ++ ++ ++ ++ ++
CA 1 +++ +++ +++ +++ ++++ ++++
CA 3 ++++ ++++ ++++ ++++ ++ ++
Dentate gyrus ++ ++ ++ ++ ++ ++
Medial habenular nucleus
Lateral habenular nucleus + + ++ ++ ++ ++
Suprachiasmatic nucleus ++ ++ ++ ++ ++ ++
Medial preoptic area ++ ++ ++ ++ ++ ++
Anteroventral periventricular nucleus + +++ + +++ +/− ++
Periventricular hypothalamic nucleus (Intermediate) + + + + +/− +/−
Peri-paraventricular hypothalamic nucleus ++ ++ ++ ++ ++ ++
Paraventricular hypothalamic nucleus +/− +/− +/− +/− + +
Supraoptic nucleus
Anterior hypothalamus +++ ++ +++ +++ ++ +
Lateral hypothalamic area + + + + + +
Arcuate nucleus +/− +/− + + +++ +++
Dorsomedial nucleus ++ ++ ++ ++ ++ ++
Tuberal nucleus + + ++ ++ + +
Ventromedial hypothalamic nucleus +/− +/− +/− +/− + +