Table 1.
Distribution of CRFR1-GFP-ir cells in the developing mouse forebrain. Density and intensity of CRFR1-GFP-ir was rated visually during developmental periods P0, P4, and P21, as having −, No label; +/−, minimal but still noticeable labeling intensity/density of cells; +, low labeling intensity/density of cells; ++, moderate labeling intensity/cell density; +++, high labeling intensity/cell density; ++++, very high labeling intensity/cell density
P0 | P4 | P21 | ||||
---|---|---|---|---|---|---|
Brain region | Male | Female | Male | Female | Male | Female |
Outer cortical layers | + + | ++ | +++ | +++ | ++ | ++ |
Middle cortical layers | + + | ++ | ++ | ++ | ++++ | ++++ |
Inner cortical layers | + | + | +++ | +++ | ++ | ++ |
Medial septum | + | + | ++ | ++ | ++ | ++ |
Lateral septum | + | + | ++ | ++ | + | + |
Diagonal band | + | + | ++ | ++ | ++ | ++ |
Bed Nucleus of the Stria Terminalis, principal nucleus | +++ | +++ | +++ | +++ | ++ | ++ |
Lateral amygdaloid nucleus | +/− | +/− | + | + | + | + |
Basolateral amygdaloid nucleus | + | + | + | + | + | + |
Basomedial amygdaloid nucleus | +++ | +++ | +++ | +++ | +++ | +++ |
Central amygdaloid nucleus | ++ | ++ | ++ | ++ | ++ | ++ |
Medial amygdaloid nucleus | +/− | +/− | + | + | + + | + + |
Cortical amygdaloid nucleus | ++ | ++ | ++ | ++ | ++ | ++ |
CA 1 | +++ | +++ | +++ | +++ | ++++ | ++++ |
CA 3 | ++++ | ++++ | ++++ | ++++ | ++ | ++ |
Dentate gyrus | ++ | ++ | ++ | ++ | ++ | ++ |
Medial habenular nucleus | − | − | − | − | − | − |
Lateral habenular nucleus | + | + | ++ | ++ | ++ | ++ |
Suprachiasmatic nucleus | ++ | ++ | ++ | ++ | ++ | ++ |
Medial preoptic area | ++ | ++ | ++ | ++ | ++ | ++ |
Anteroventral periventricular nucleus | + | +++ | + | +++ | +/− | ++ |
Periventricular hypothalamic nucleus (Intermediate) | + | + | + | + | +/− | +/− |
Peri-paraventricular hypothalamic nucleus | ++ | ++ | ++ | ++ | ++ | ++ |
Paraventricular hypothalamic nucleus | +/− | +/− | +/− | +/− | + | + |
Supraoptic nucleus | − | − | − | − | − | − |
Anterior hypothalamus | +++ | ++ | +++ | +++ | ++ | + |
Lateral hypothalamic area | + | + | + | + | + | + |
Arcuate nucleus | +/− | +/− | + | + | +++ | +++ |
Dorsomedial nucleus | ++ | ++ | ++ | ++ | ++ | ++ |
Tuberal nucleus | + | + | ++ | ++ | + | + |
Ventromedial hypothalamic nucleus | +/− | +/− | +/− | +/− | + | + |