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. Author manuscript; available in PMC: 2020 May 1.
Published in final edited form as: J Intern Med. 2019 Mar 14;285(5):524–532. doi: 10.1111/joim.12886

Figure 2.

Figure 2

The macrophage balance. Macrophages can exert a dual function in the tumor microenvironment. In established clinical tumors the pro- tumor function of TAM prevail. Macrophages serve as a paradigm for tumor promoting inflammation