Figure 2.

Representative examples of the raw data from patients undergoing successful (left column, outcome = 1) and unsuccessful (right column, outcome = 0) anaesthetic weans. Top row: Intravenous anaesthetic infusion rate versus time. Time = 0 indicates the time of cessation of intravenous anaesthesia. Rows 2–5: Frequency-based quantitative metrics (relative alpha power, relative delta power, relative theta power, and alpha/delta ratio) versus time. Rows 6–13: Spatial-correlation-based quantitative metrics (network density, number of independent components, mean clustering coefficient, characteristic path length, number of non-trivial components, size of the largest independent component, clustering coefficient of the largest component, and characteristic path length of the largest component) versus time. In both the successful and unsuccessful cases, the alpha/delta ratio rises as intravenous anaesthesia is discontinued. In the successful but not the unsuccessful case, as intravenous anaesthesia is withdrawn, there is a gradual rise in network density, clustering coefficient, characteristic path length, and size of the largest component and fall in the number of independent components as network connectivity rises.