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. 2020 Apr 5;7(1):e001041. doi: 10.1136/openhrt-2019-001041

Table 2.

The correlation between %changes of (%Δ) markers during hospitalisation

Entire cohort PIIINP at discharge P4NP 7S at discharge %ΔPIIINP %ΔP4NP 7S
Value Low High P value Low High P value Coefficient P value Coefficient P value
%ΔT-Bil −20.0% −20.0% −20.0% 0.84 −16.7% −22.2% 0.015 −0.11 0.043 0.09 0.091
%ΔAST −20.8% −26.9% −12.5% 0.0001 −25.0% −15.4% 0.0026 0.07 0.19 0.03 0.51
%ΔALP −6.9% −8.9% −4.0% 0.051 −11.3% −1.3% <0.0001 0.26 <0.0001 0.11 0.038
%Δγ−GTP −9.7% −16.3% −1.5% <0.0001 −11.2% −5.7% 0.012 0.16 0.0086 0.07 0.22
%ΔAlbumin 2.6% 5.0% 0.0% 0.0001 3.1% 0.0% 0.011 −0.17 0.003 −0.01 0.78
%ΔeGFR −7.1% −4.3% −10.3% 0.005 −9.4% −4.7% 0.0037 −0.13 0.024 0.07 0.1862
%ΔBNP −56.7% −58.8% −54.6% 0.62 −66.4% −47.8% <0.0001 −0.03 0.59 0.31 <0.0001
%ΔPIIINP −1.5% −9.9% 7.2% <0.0001 −4.7% 2.4% 0.038 N/A 0.16 0.0047
%ΔP4NP 7S −15.6% −16.9% −13.5% 0.045 −20.7% −8.2% <0.0001 0.16 0.0047 N/A

ALP, alkaline phosphatase; AST, aspartate aminotransferase; BNP, brain natriuretic peptide; eGFR, estimated glomerular filtration rate; γ-GTP, γ-glutamyltransferase; PIIINP, N-terminal propeptide of procollagen type III; P4NP 7S, 7S domain of the collagen type IV N-terminal propeptide; T-Bil, total bilirubin.