Table 2.
The correlation between %changes of (%Δ) markers during hospitalisation
Entire cohort | PIIINP at discharge | P4NP 7S at discharge | %ΔPIIINP | %ΔP4NP 7S | |||||||
Value | Low | High | P value | Low | High | P value | Coefficient | P value | Coefficient | P value | |
%ΔT-Bil | −20.0% | −20.0% | −20.0% | 0.84 | −16.7% | −22.2% | 0.015 | −0.11 | 0.043 | 0.09 | 0.091 |
%ΔAST | −20.8% | −26.9% | −12.5% | 0.0001 | −25.0% | −15.4% | 0.0026 | 0.07 | 0.19 | 0.03 | 0.51 |
%ΔALP | −6.9% | −8.9% | −4.0% | 0.051 | −11.3% | −1.3% | <0.0001 | 0.26 | <0.0001 | 0.11 | 0.038 |
%Δγ−GTP | −9.7% | −16.3% | −1.5% | <0.0001 | −11.2% | −5.7% | 0.012 | 0.16 | 0.0086 | 0.07 | 0.22 |
%ΔAlbumin | 2.6% | 5.0% | 0.0% | 0.0001 | 3.1% | 0.0% | 0.011 | −0.17 | 0.003 | −0.01 | 0.78 |
%ΔeGFR | −7.1% | −4.3% | −10.3% | 0.005 | −9.4% | −4.7% | 0.0037 | −0.13 | 0.024 | 0.07 | 0.1862 |
%ΔBNP | −56.7% | −58.8% | −54.6% | 0.62 | −66.4% | −47.8% | <0.0001 | −0.03 | 0.59 | 0.31 | <0.0001 |
%ΔPIIINP | −1.5% | −9.9% | 7.2% | <0.0001 | −4.7% | 2.4% | 0.038 | N/A | 0.16 | 0.0047 | |
%ΔP4NP 7S | −15.6% | −16.9% | −13.5% | 0.045 | −20.7% | −8.2% | <0.0001 | 0.16 | 0.0047 | N/A |
ALP, alkaline phosphatase; AST, aspartate aminotransferase; BNP, brain natriuretic peptide; eGFR, estimated glomerular filtration rate; γ-GTP, γ-glutamyltransferase; PIIINP, N-terminal propeptide of procollagen type III; P4NP 7S, 7S domain of the collagen type IV N-terminal propeptide; T-Bil, total bilirubin.