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. 2020 Mar 30;8(1):e000371. doi: 10.1136/jitc-2019-000371

Figure 1.

Figure 1

Cumulative incidence irAEs plots for mRCC and mUC: irAEs all grades (A), irAEs grades ≥3 (B). The cumulative incidence of irAEs for mRCC and mUC were similar for all irAEs, irrespective of grade of toxicity. The cumulative incidence of irAE was 32.1% (95% CI: 27.7% to 36.5%) at 6 months, 38.8% (95% CI: 34.1% to 43.4%) at 1 year, and 46.3% (95% CI: 40.4% to 52.2%) at 5 years (A). The cumulative incidence of a grade ≥3 irAE was 7.5% (95% CI: 5.0% to 10.0%) at 6 months, 10.6% (95% CI: 7.6% to 13.6%) at 1 year, and 11.7% (95% CI: 8.3% to 15.0%) at 5 years (B). irAE, immune-related adverseevent; mRCC, metastatic urothelialcarcinoma; mUC, metastatic renal cell carcinoma.