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. 2020 Mar 30;8(1):e000371. doi: 10.1136/jitc-2019-000371

Table 3.

Monthly incidence and conditional probability of irAEs

Landmark month Patients alive on landmark day with no prior irAE, N Patients with irAEs in next 30 days, n (%) Patients with irAEs at any time in the future, n (%) 95% CI for future irAE at any time
0 470 47 (10.0) 186 (39.6) 35.1 to 44.2
1 415 28 (6.8) 139 (33.5) 29.0 to 38.3
2 358 25 (7.0) 111 (31.0) 26.3 to 36.1
3 312 13 (4.2) 86 (27.6) 22.7 to 32.9
4 270 19 (7.0) 73 (27.0) 21.8 to 32.8
5 222 11 (5.0) 54 (24.3) 18.8 to 30.5
6 193 11 (5.7) 43 (22.3) 16.6 to 28.8
7 176 5 (2.8) 32 (18.2) 12.8 to 24.7
8 163 6 (3.7) 27 (16.6) 11.2 to 23.2
9 146 2 (1.4) 21 (14.4) 9.1 to 21.1
10 132 2 (1.5) 19 (14.4) 8.9 to 21.6
11 118 0 (0.0) 17 (14.4) 8.6 to 22.1
12 109 3 (2.8) 17 (15.6) 9.4 to 23.8

CI, cumulative incidence; irAEs, immune-related adverse events.