Table 2. Univariable and multivariable linear regression analyses of the predictors of headache-related impact in migraine.

	Univariable analysis					Multivariable analysis
	B	SE	β	95% CI	p	B	SE	β	95% CI	p
Age	-0.067	0.032	-0.074	-0.129 to -0.004	0.038	-0.047	0.036	-0.053	-0.118 to 0.024	0.194
Female sex	-0.126	0.985	-0.005	-2.058 to 1.807	0.899	0.815	0.985	0.030	-1.119 to 2.749	0.408
Disease duration	-0.028	0.042	-0.026	-0.110 to 0.053	0.493	-0.007	0.043	-0.006	-0.092 to 0.078	0.869
Headache frequency	0.209	0.039	0.188	0.132 to 0.285	<0.001	0.130	0.043	0.116	0.045 to 0.216	0.003
Chronic migraine*	3.713	0.837	0.157	2.070 to 5.356	<0.001	-	-	-	-	-
Headache severity	1.798	0.263	0.238	1.282 to 2.313	<0.001	1.335	0.282	0.174	0.783 to 1.888	<0.001
PSQI	0.875	0.110	0.274	0.659 to 1.090	<0.001	0.466	0.133	0.146	0.205 to 0.728	0.001
HADS-D score	0.622	0.103	0.215	0.420 to 0.825	<0.001	0.261	0.134	0.092	-0.002 to 0.523	0.052
HADS-A score	0.594	0.102	0.209	0.394 to 0.793	<0.001	0.172	0.136	0.061	-0.095 to 0.440	0.206
Allodynia	3.566	1.011	0.126	1.581 to 5.551	<0.001	1.205	1.063	0.042	-0.882 to 3.293	0.257

^*Chronic migraine was not included in the multivariable model because the disease duration, headache frequency, and chronic migraine are closely linked.

B: unstandardized regression coefficient, CI: confidence interval, HADS-A: Hospital Anxiety and Depression Scale–Anxiety, HADS-D: Hospital Anxiety and Depression Scale–Depression, PSQI: Pittsburgh Sleep Quality Index, SE: standard error of B, β: standardized regression coefficient.