Table 3. Structure and implementation of the tablet-based application and workbooks for cognitive training.

	Cognitive training application	Workbook for cognitive training
Training cognitive domain	Memory, frontal function, attention, visuospatial function, and calculation.	Memory, frontal function, attention, visuospatial function, calculation, and language.
Training memory strategies	Spaced retrieval, visual imagery, story making, association, chunking, categorization, sequencing, acronyms, keyword method, rehearsal, and rhyming.	Spaced retrieval, visual imagery, story making, association, chunking, categorization, sequencing, acronyms, keyword method, rehearsal, and rhyming.
Structure	The tablet-based cognitive training application has 48 memory tasks, 12 frontal/attention tasks, 4 visuospatial tasks, and 4 calculation tasks.	There are 48 workbooks, each of which consists of 3 or 4 pages for 1 memory task and 2 or 3 pages for tasks in different cognitive domains.
Level of difficulty	Ten levels of difficulty in all except memory tasks, which have a single level of difficulty.	Two levels of difficulty
Session configuration	1. Welcome, and checking homework (10 minutes).	1. Welcome, and checking homework (10 minutes).
	2. Four tasks using the tablet application: one memory task (20 minutes), two frontal function/attention tasks (10 minutes), and one visuospatial or calculation task (5 minutes).	2. Cognitive training using one workbook (30–35 minutes).
	3. Wrap-up (5 minutes).	3. Wrap-up (5 minutes).
Therapist	Psychologist, occupational therapist, or study nurse.	Psychologist, occupational therapist, or study nurse.
Adherence	Adherence is assessed using the administrative website that stores information such as whether a participant uses cognitive content.	Adherence is assessed by checking the workbook.