Table 2. Demographics and clinical characteristics of the aMCI and NC subgroups.
| Variable | Verbal-aMCI (n=12) | Visual-aMCI (n=10) | Both-aMCI (n=16) | NC (n=37) |
|---|---|---|---|---|
| Age, years | 71.0±11.42* | 71.5±5.02* | 68.6±6.78 | 64.6±11.7 |
| Age at onset, years | 70.2±10.19 | 68.2±5.18 | 65.7±7.16 | 64.4±11.41 |
| Sex, female | 8 (66.7) | 8 (80.0) | 11 (68.8) | 20 (54.1) |
| Education, years | 6.29±3.36* | 8.80±5.15 | 8.34±5.01* | 11.95±4.47 |
| Disease duration, months | 28.0±16.24 | 28.8±19.55 | 34.0±13.44 | - |
| MMSE score | 24.3±3.81* | 26.1±2.13* | 23.3±4.86* | 28.4±1.76 |
| CDR-SOB score | 1.25±0.89* | 0.80±0.58* | 2.43±1.50* | 0.00±0.00 |
| APOE ε4 carrier | 4 (33.3) | 2 (20.0) | 8 (50.0)* | 8 (21.6) |
| Amyloid positivity | 3/5 (60.0)* | 2/3 (66.7)* | 7/11 (63.6)* | 0 (0) |
Data are mean±SD values for continuous variables and n (%) values for categorical variables.
*p<0.05 versus NC in independent t-test for continuous variables and chi-square test for categorical variables.
aMCI: amnestic MCI, Both-aMCI: MCI with both visual and verbal memory impairment, CDR-SOB: Clinical Dementia Rating–Sum of Boxes, MCI: mild cognitive impairment, MMSE: Mini Mental State Examination, NC: normal cognition, Verbal-aMCI: MCI with verbal memory impairment, Visual-aMCI: MCI with visual memory impairment.