Table 3.
Effects of 3 mg/g hispidin‐enriched Sanghuangporus sanghuang mycelia on clinical pathology parameters in single‐dose acute toxicity study
| Parameters | Control | PL mycelia |
|---|---|---|
| Male | ||
| Day 0 weight (g) | 35.2 ± 0.6 | 36.3 ± 0.6 |
| Day 7 weight (g) | 37.8 ± 0.9 | 38.3 ± 0.9 |
| ALT (U/L) | 51.8 ± 2.5 | 58.3 ± 5.5 |
| AST (U/L) | 105.6 ± 6.2 | 108.7 ± 7.5 |
| BUN (mg/dl) | 29 ± 0.6 | 20.2 ± 1.1* |
| Female | ||
| Day 0 weight (g) | 27 ± 0.4 | 26.6 ± 0.6 |
| Day 7 weight (g) | 27.5 ± 0.4 | 26.7 ± 0.4 |
| ALT (U/L) | 56.6 ± 3.1 | 52.5 ± 1.6 |
| AST (U/L) | 108.6 ± 7.7 | 87.7 ± 3.5 |
| BUN (mg/dl) | 20.8 ± 1.7 | 17.5 ± 0.8 |
Results are expressed as mean ± SD (n = 5) and analyzed by one‐way ANOVA and Duncan's multiple range test.
Abbreviations: ALT, alanine aminotransferase; AST, aspartate aminotransferase; BUN, blood urea nitrogen.
*
Significantly different from the control at p < .05.