Table 3.

Adjusted Odds ratio with 95% confidence interval per half year for each study endpoint

	Model 1*		Model 2†		Model 3‡
	Odds ratio (95% CI)	P-value	Odds ratio (95% CI)	P-value	Odds ratio (95% CI)	P-value
Successful reperfusion
2010–2014 (per half year)	1.159 (1.125–1.193)	<0.001	–	–	–	–
2010–2012 (per half year)	1.109 (1.037–1.185)	0.002	–	–	–	–
2013–2014 (per half year)	1.578 (1.426–1.746)	<0.001	–	–	–	–
Complete reperfusion
2010–2014 (per half year)	1.164 (1.126–1.202)	<0.001	–	–	–	–
2010–2012 (per half year)	1.012 (0.934–1.097)	0.767	–	–	–	–
2013–2014 (per half year)	1.606 (1.446–1.783)	<0.001	–	–	–	–
Favorable outcome
2010–2014 (per half year)	1.077 (1.042–1.114)	<0.001	1.026 (0.991–1.063)	0.151	1.029 (0.993–1.066)	0.118
2010–2012 (per half year)	1.09 (0.932–1.093)	0.824	0.967 (0.888–1.053)	0.444	0.982 (0.900–1.070)	0.672
2013–2014 (per half year)	1.227 (1.103–1.366)	<0.001	1.075 (0.958–1.206)	0.217	1.078 (0.960–1.212)	0.204
Death
2010–2014 (per half year)	0.954 (0.911–0.999)	0.044	0.981 (0.935–1.028)	0.418	0.978 (0.932–1.027)	0.378
2010–2012 (per half year)	0.946 (0.852–1.051)	0.303	0.950 (0.852–1.060)	0.359	0.920 (0.823–1.028)	0.142
2013–2014 (per half year)	0.767 (0.656–0.896)	0.001	0.826 (0.703–0.971)	0.02	0.814 (0.692–0.957)	0.013

^*Adjusted for preprocedural variables including age, sex, premorbid modified Rankin Scale score, large-artery atherosclerosis, occlusion of internal carotid artery or basilar artery, baseline National Institutes of Health Stroke Scale score, onset-to-treatment time, and intravenous recombinant tissue-plasminogen activator.

^†Adjusted for preprocedural variables and successful reperfusion.

^‡Adjusted for preprocedural variables, successful reperfusion and intracranial hemorrhagic complications. CI: confidence interval.