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. 2020 Apr 21;10:6726. doi: 10.1038/s41598-020-63802-1

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Glycated hemoglobin (HbA1c) levels after acute myocardial infarction and the association of this variable with prognosis. HbA1c was measured continuously throughout the follow-up period (A). The adjusted hazard ratio according to the individual mean HbA1C level for each patient, illustrated by a J-shaped restricted cubic spline curve for all-cause mortality (B). Patients were classified into three groups according to the mean HbA1c levels: <6.0%, ≥6% to <7.5%, and ≥7.5%; each group maintained a constant HbA1c level throughout the follow-up period. The size of the circle indicates the number of patients included at each time point, and the linear lines indicate the average and standard deviation (C). The cumulative 5-year survival rate differed significantly between the three groups (D).