Table 2.
Cox proportional hazard analysis of covariates for all-cause mortality in group B (HbA1c ≥ 6%, <7.5%) vs. C (HbA1c ≥ 7.5%).
| Univariable | Multivariable | |||||
|---|---|---|---|---|---|---|
| HR | CI | p | HR | CI | P | |
| HbA1c (>=7.5) | 1.72 | 1.21–2.45 | 0.003 | 1.55 | 1.02–2.34 | 0.038 |
| Age | 1.09 | 1.07–1.11 | <.001 | 1.07 | 1.04–1.10 | <0.001 |
| Sex (Male) | 0.68 | 0.47–0.98 | 0.037 | 1.48 | 0.99–2.22 | 0.059 |
| BMI, kg/m2 | 0.83 | 0.79–0.88 | <.001 | 0.91 | 0.85–0.97 | 0.002 |
| Hypertension | 1.8 | 1.21–2.70 | 0.004 | 1.47 | 0.95–2.29 | 0.086 |
| Dyslipidemia | 0.6 | 0.38–0.96 | 0.035 | 0.56 | 0.33–0.94 | 0.029 |
| STEMI | 0.61 | 0.42–0.88 | 0.007 | |||
| Previous CVD | 2.39 | 1.62–3.53 | <.001 | 2.15 | 1.40–3.28 | <0.001 |
| Beta-blockers | 0.55 | 0.38–0.78 | 0.001 | |||
| RAS inhibitors | 0.5 | 0.34–0.74 | <.001 | 0.54 | 0.36–0.81 | 0.003 |
| Statin | 0.47 | 0.30–0.72 | <.001 | |||
| OHA | 0.55 | 0.39–0.79 | 0.001 | |||
| Insulin | 2.45 | 1.56–3.24 | <.001 | 1.87 | 1.20–2.93 | 0.006 |
| Creatinine, mg/dl | 1.15 | 1.07–1.23 | <.001 | 1.11 | 0.99–1.23 | 0.068 |
| LVEF (<40%) | 2.62 | 1.77–3.89 | <.001 | 1.42 | 0.92–2.21 | 0.117 |
| New DM | 0.73 | 0.47–1.13 | 0.160 | 1.44 | 0.88–2.34 | 0.142 |
| GRACE | 1.02 | 1.02–1.03 | <.001 | 1.01 | 1.00–1.02 | 0.005 |
BMI, body mass index; STEMI, ST-elevated myocardial infarction; RAS, renin–angiotensin system; CCB, calcium channel blocker; OHA, oral hypoglycemic agent; LVEF, left ventricle ejection fraction.