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. 2020 Apr 21;10:6761. doi: 10.1038/s41598-020-63681-6

Table 3.

Univariate and multivariate analysis factors influencing focal LC defects.

Univariate Multivariate
Variables Odds Ratio 95% CI P value Odds Ratio 95% CI P value
Age, per 1-year older 1.000 0.966–1.036 0.979
Gender, female 1.619 0.780–3.363 0.196
Presence of DM 1.000 0.274–3.654 1.000
Presence of HTN 0.617 0.279–1.362 0.232
SBP, mmHg 0.971 0.942–1.002 0.065 0.988 0.951–1.026 0.522
DBP, mmHg 0.979 0.938–1.021 0.317
MAP, mmHg 0.968 0.928–1.010 0.131
MPP, mmHg 0.975 0.920–1.034 0.407
Scan IOP, mmHg 0.853 0.716–1.015 0.074 0.875 0.706–1.085 0.224
Presence of MvD 5.758 2.332–14.215 <0.001 4.824 1.779–13.083 0.002
Area of MvD, mm2 18.873 2.387–149.250 0.005 0.687 0.151–17.557 0.687
Axial length, mm 1.023 0.743–1.409 0.877
Central cornea thickness, μm 0.998 0.987–1.009 0.703
Global RNFL thickness, μm 1.003 0.977–1.030 0.803
Visual field MD, dB 1.003 0.947–1.062 0.921
Visual field PSD, dB 1.044 0.958–1.137 0.330
Average LCCI 0.425 0.298–0.606 <0.001 0.438 0.302–0.636 <0.001

DM = diabetes mellitus; HTN = hypertension; SBP = systolic blood pressure; DBP = diastolic blood pressure; MAP = mean arterial pressure; MPP = mean perfusion pressure; IOP = intraocular pressure; MvD = microvasculature dropout; RNFL = retinal nerve fiber layer; MD = mean deviation; PSD = pattern standard deviation.

Only variables with P < 0.1 on univariate analysis were included in the multivariate model.

Statistical significant factors are shown in boldface.