Table 3.
Univariate and multivariate analysis factors influencing focal LC defects.
| Univariate | Multivariate | |||||
|---|---|---|---|---|---|---|
| Variables | Odds Ratio | 95% CI | P value | Odds Ratio | 95% CI | P value |
| Age, per 1-year older | 1.000 | 0.966–1.036 | 0.979 | |||
| Gender, female | 1.619 | 0.780–3.363 | 0.196 | |||
| Presence of DM | 1.000 | 0.274–3.654 | 1.000 | |||
| Presence of HTN | 0.617 | 0.279–1.362 | 0.232 | |||
| SBP, mmHg | 0.971 | 0.942–1.002 | 0.065 | 0.988 | 0.951–1.026 | 0.522 |
| DBP, mmHg | 0.979 | 0.938–1.021 | 0.317 | |||
| MAP, mmHg | 0.968 | 0.928–1.010 | 0.131 | |||
| MPP, mmHg | 0.975 | 0.920–1.034 | 0.407 | |||
| Scan IOP, mmHg | 0.853 | 0.716–1.015 | 0.074 | 0.875 | 0.706–1.085 | 0.224 |
| Presence of MvD | 5.758 | 2.332–14.215 | <0.001 | 4.824 | 1.779–13.083 | 0.002 |
| Area of MvD, mm2 | 18.873 | 2.387–149.250 | 0.005 | 0.687 | 0.151–17.557 | 0.687 |
| Axial length, mm | 1.023 | 0.743–1.409 | 0.877 | |||
| Central cornea thickness, μm | 0.998 | 0.987–1.009 | 0.703 | |||
| Global RNFL thickness, μm | 1.003 | 0.977–1.030 | 0.803 | |||
| Visual field MD, dB | 1.003 | 0.947–1.062 | 0.921 | |||
| Visual field PSD, dB | 1.044 | 0.958–1.137 | 0.330 | |||
| Average LCCI | 0.425 | 0.298–0.606 | <0.001 | 0.438 | 0.302–0.636 | <0.001 |
DM = diabetes mellitus; HTN = hypertension; SBP = systolic blood pressure; DBP = diastolic blood pressure; MAP = mean arterial pressure; MPP = mean perfusion pressure; IOP = intraocular pressure; MvD = microvasculature dropout; RNFL = retinal nerve fiber layer; MD = mean deviation; PSD = pattern standard deviation.
Only variables with P < 0.1 on univariate analysis were included in the multivariate model.
Statistical significant factors are shown in boldface.