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. 2020 Apr 21;10:6675. doi: 10.1038/s41598-020-63767-1

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Particle size distribution analysis of PLGA-NPs by DLS for empty (A) and TAC-loaded (B); In vitro release profile of TAC-loaded PLGA-NPs in PBS at pH 7.4 (C); SEM image of TAC-loaded PLGA-NPs (D) [Scale bar represents 500 nm].