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. 2020 Apr 21;11:1770. doi: 10.1038/s41467-020-15553-w

Fig. 3. Summary Mendelian randomization (MR) estimates of leisure sedentary behaviours on CAD.

Fig. 3

Summary MR estimates of the causal association between (a) leisure television watching, (b) leisure computer use and (c) driving on coronary artery disease were derived from the main inverse-variance-weighted (MR-IVW), MR-Egger, MR-IVW excluding potentially pleiotropic single-nucleotide polymorphisms (SNPs) through education, MR-IVW excluding potentially pleiotropic SNPs through any trait, MR pleiotropy residual sum and outlier (MR-PRESSO), outlier-corrected MR-PRESSO, multivariable Mendelian randomization adjusted for educational years, weighted median and weighted mode-based estimator methods. On the X-axis, odds ratios are shown and data are represented as odds ratio and 95% confidence intervals. We considered two-sided P < 0.05 statistically significant, no adjustments were made for multiple testing. OR odds ratio, CI confidence interval.