Table 1.
Patients and tumor clinicopathologic characteristics.
Variables | Number of patients | Low TIL levels | High TIL levels | p-value |
---|---|---|---|---|
(<50%) | (>50%) | |||
(n = 43) | (n = 32) | (n = 11) | ||
Patients (n) | 43 | 32 | 11 | |
Patient age, years (mean ± SD) | 52.3 ± 14.4 | 51.6 ± 13.6 | 54.8 ± 17 | 0.534 |
Lymph node metastasis | ||||
Negative | 21 (48.8%) | 16 (50%) | 5 (45.5%) | 0.795 |
Positive | 22 (51.2%) | 16 (50%) | 6 (55.5%) | |
Histologic grade | ||||
Low | 0 | 0 | 0 | |
Moderate | 11 (25.6%) | 5 (15.6%) | 5 (45.5%) | 0.043 |
High | 32 (74.4%) | 27 (84.4%) | 6 (54.5%) | |
Ki-67 | ||||
Low (<14%) | 17 (39.5%) | 16 (50%) | 10 (9.0%) | 0.017 |
High (>14%) | 26 (60.5%) | 16 (50%) | 1 (91.0%) | |
EGFR | ||||
Negative | 28 (65.1%) | 22 (68.8%) | 6 (54.5%) | 0.394 |
Positive | 15 (34.9%) | 10 (31.2%) | 5 (45.5%) | |
P53 | ||||
Negative | 16 (37.2%) | 13 (40.6%) | 3 (27.3%) | 0.340 |
Positive | 27 (62.8%) | 19 (59.4%) | 8 (72.7%) |
EGFR, epidermal growth factor receptor; SD, standard deviation; TIL, tumor-infiltrating lymphocyte.