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. 2020 Apr 15;10:412. doi: 10.3389/fonc.2020.00412

Table 2.

Analysis of radiomics features between low and high TIL levels.

Radiomics features Low TIL levels High TIL levels p-value
(<50%) (>50%)
(n = 32) (n = 11)
Uniformity (MLO)
 Mean 0.017 0.014 0.023
 Range 0.009–0.027 0.009–0.025
Variance (CC)
 Mean 260,776.234 328,611.123 0.046
 Range 69,059.883–638,614.685 129,976.869–592,881.928
GLCM correlation (MLO)
 Mean 0.959 0.967 0.020
 Range 0.926–0.989 0.925–0.983
GLCM autocorrelation (CC)
 Mean 5,032.505 7,170.002 0.010
 Range 1,367.669–8,852.751 3,287.865–10,759.123
GLDM low gray level emphasis (CC)
 Mean 0.00057 0.00038 0.041
 Range 0.00019–0.0014 0.00014–0.00063
NGTDM contrast (MLO)
 Mean 0.133 0.180 0.090
 Range 0.054–0.323 0.071–0.244

CC, craniocaudal; GLCM, grayscale symbiosis matrix; GLDM, gray level difference matrix; MLO, mediolateral oblique; NGTDM, neighborhood gray-tone difference matrix; TIL, tumor-infiltrating lymphocyte.