Table 3.
The correlation analysis of clinicopathologic characteristics and radiomics features.
| Features | Uniformity (MLO) | Variance (CC) | GLCM correlation (MLO) | GLCM autocorrelation (CC) | GLDM low gray level emphasis (CC) | NGTDM contrast (MLO) |
|---|---|---|---|---|---|---|
| Ki-67 | ||||||
| p-value | 0.0303* | 0.0062* | 0.4950 | 0.0058* | 0.1757 | 0.1240 |
| r-value | 0.26 | −0.28 | 0.058 | −0.4* | 0.13 | −0.21 |
| Histologic grade | ||||||
| p-value | 0.2406 | 0.2875 | 0.2778 | 0.3813 | 0.3813 | 0.2588 |
| r-value | 0.07 | −0.0061 | −0.067 | −0.11 | 0.14 | −0.058 |
| Lymph node metastasis | ||||||
| p-value | 0.4758 | 0.4087 | 0.2149 | 0.4758 | 0.4855 | 0.2923 |
| r-value | −0.069 | 0.001 | −0.093 | −0.032 | −0.056 | 0.11 |
| Age | ||||||
| p-value | 0.1732 | 0.0070* | 0.0342* | 0.0519 | 0.2278 | 0.1732 |
| r-value | 0.069 | 0.44 | −0.26 | 0.17 | −0.028 | −0.027 |
| EGFR | ||||||
| p-value | 0.0647 | 0.4043 | 0.3750 | 0.4443 | 0.2338 | 0.0404* |
| r-value | 0.19 | −0.027 | 0.099 | −0.023 | 0.031 | −0.29 |
| P53 | ||||||
| p-value | 0.4450 | 0.4057 | 0.3485 | 0.3767 | 0.3767 | 0.3672 |
| r-value | 0.088 | 0.054 | −0.11 | 0.022 | 0.14 | 0.1 |
*
Significant differences.
EGFR, epidermal growth factor receptor; CC, craniocaudal; GLCM, grayscale symbiosis matrix; GLDM, gray level difference matrix; MLO, mediolateral oblique; NGTDM, neighborhood gray-tone difference matrix.