TABLE 2.
MIC and blaCMY–2 expression levels in the 11 CMY-2-producing E. coli ST405 isolates.
| Isolate | Household | Species | Coproducing ESBL/AmpC |
MIC |
Relative CMY-2 transcript level ± SD compared to E118 strain | ||
| FOX | CTX | CAZ | |||||
| E686 | H11h2 | Human | No | 64 | 16 | 32 | 0.223 ± 0.003 |
| E911 | H5h9 | Human | No | 64 | 32 | 64 | 0.188 ± 0.007 |
| E933 | H6h4 | Human | No | 64 | 32 | 64 | 0.307 ± 0.024 |
| E118 | (3)* | Dog | No | 128 | 32 | 64 | 1 |
| E797 | H11h1 | Dog | No | 128 | 32 | 64 | 1.385 ± 0.059 |
| E891 | H6h8 | Dog | No | 128 | 64 | 256 | 1.594 ± 0.079 |
| E893 | H7h15 | Dog | CTX-M-14 | 128 | 256 | 64 | 1.935 ± 0.139 |
| E597 | H6h7 | Dog | No | 256 | 32 | 64 | 5.389 ± 0.238 |
| E777 | H7h2 | Dog | No | 256 | 64 | 128 | 7.374 ± 0.312 |
| E858 | H6h5 | Dog | No | 256 | 32 | 64 | 4.221 ± 0.530 |
| E941 | H15h2 | Dog | No | 256 | 32 | 64 | 5.324 ± 0.362 |
Abbreviations: Ct, cycle threshold; ST, sequence type; FOX, cefoxitin; CTX, cefotaxime; CAZ, ceftazidime; SD, standard deviation. An asterisk (*) indicates Reference 3 in this study.