Table 4.
Upregulated titin phosphosites (log2 ratio KO/WT > 0.37).
| Position within titin | UniProt identifyer | Log2 ratio (KO/WT) | –Log 10 p-value KO/WT | Charge | Multiplicity | Localization probability | Classification of phosphosite | Sequence window |
|---|---|---|---|---|---|---|---|---|
| T314 | A2ASS6 | 0.386936 | 1.09573 | 2 | 1 | 0.982868 | Class 1 | TPSPVRSVSPAGRISTSPIRSVKSPLLIRKT |
| T10276 | A2ASS6 | 0.395205 | 0 | 3 | 1 | 0.637793 | Class 2 | EVQKKVVTEEKIAIITQREESPPPAVPEIPK |
| S315 | A2ASS6 | 0.40279 | 1.45166 | 2 | 1 | 0.997856 | Class 1 | PSPVRSVSPAGRISTSPIRSVKSPLLIRKTQ |
| S264 | A2ASS6 | 0.419615 | 1.33152 | 2 | 2 | 1 | Class 1 | PHKTPPRIPPKPKSRSPTPPSIAAKAQLARQ |
| S35038 | A2ASS6 | 0.429709 | 0.499475 | 2 | 1 | 0.987556 | Class 1 | VVLKTSSDVSLHGSVSSQSVQMSASKQEASF |
| S262 | A2ASS6 | 0.433659 | 0.711028 | 2 | 2 | 1 | Class 1 | QLPHKTPPRIPPKPKSRSPTPPSIAAKAQLA |
| S23788 | A2ASS6 | 0.438542 | 0 | 2 | 1 | 0.993369 | Class 1 | KNYIVEKRESTRKAYSTVATNCHKTSWKVDQ |
| S1527 | A2ASS6 | 0.44247 | 0 | 3 | 1 | 0.86319 | Class 1 | VIKEDGTQSLIIVPASPSDSGEWTVVAQNRA |
| S31025 | A2ASS6 | 0.474799 | 0 | 3 | 1 | 0.838063 | Class 1 | GLGVPVESEPIVARNSFTIPSQPGIPEEVGA |
| S834 | A2ASS6 | 0.503759 | 0.543576 | 2 | 1 | 0.99992 | Class 1 | VSKISVPKTEHGYEASIAGSAIATLQKELSA |
| S307 | A2ASS6 | 0.509144 | 3.60898 | 2 | 2 | 1 | Class 1 | VRHVRAPTPSPVRSVSPAGRISTSPIRSVKS |
| T314 | A2ASS6 | 0.608677 | 0 | 2 | 2 | 0.982868 | Class 1 | TPSPVRSVSPAGRISTSPIRSVKSPLLIRKT |
| S774 | A2ASS6 | 0.620881 | 0.40983 | 2 | 1 | 0.98142 | Class 1 | HVVPQAVKPAVIQAPSETHIKTTDQMGMHIS |
| S879 | A2ASS6 | 0.704194 | 0 | 3 | 2 | 0.998042 | Class 1 | TVKPGETRVRAEPTPSPQFPFADMPPPDTYK |
| S10281 | A2ASS6 | 0.719508 | 0.777963 | 3 | 1 | 0.999995 | Class 1 | VVTEEKIAIITQREESPPPAVPEIPKKKVPE |
| S262 | A2ASS6 | 0.720452 | 2.29218 | 2 | 3 | 1 | Class 1 | QLPHKTPPRIPPKPKSRSPTPPSIAAKAQLA |
| S264 | A2ASS6 | 0.767076 | 2.14935 | 2 | 3 | 1 | Class 1 | PHKTPPRIPPKPKSRSPTPPSIAAKAQLARQ |
| T266 | A2ASS6 | 0.767076 | 2.14935 | 2 | 3 | 1 | Class 1 | KTPPRIPPKPKSRSPTPPSIAAKAQLARQQS |
| S799 | A2ASS6 | 0.787488 | 0 | 3 | 1 | 0.834492 | Class 1 | MGMHISSQVKKTTDISTERLVHVDKRPRTAS |
| S12871 | A2ASS6 | 0.829341 | 1.09019 | 3 | 1 | 1 | Class 1 | AKPKGPIKGVAKKTPSPIEAERKKLRPGSGG |
| S12884 | A2ASS6 | 0.94305 | 0.52056 | 3 | 1 | 1 | Class 1 | TPSPIEAERKKLRPGSGGEKPPDEAPFTYQL |
| S12871 | A2ASS6 | 0.981417 | 0.3495 | 3 | 2 | 1 | Class 1 | AKPKGPIKGVAKKTPSPIEAERKKLRPGSGG |
| T12869 | A2ASS6 | 0.981417 | 0.3495 | 3 | 2 | 1 | Class 1 | EAAKPKGPIKGVAKKTPSPIEAERKKLRPGS |
| S838 | A2ASS6 | 1.20302 | 0 | 3 | 1 | 0.999952 | Class 1 | SVPKTEHGYEASIAGSAIATLQKELSATSST |
| S32133 | A2ASS6 | 1.4809 | 0.355789 | 2 | 1 | 0.791719 | Class 1 | PEPPSNPPEVLDVTKSSVSLSWSRPKDDGGS |
A-band.