TABLE 1.
Population characteristics.
| Ferritin <=1500 μ G/L (N = 153) | Ferritin > 1500 μ G/L (N = 145) | P-value | |
| Year of transplant median (range) [IQR] | 2016 (2014–2018)[2015–2017] | 2015 (2014–2018)[2015–2016] | 0.6 |
| Patient age (years) Median (range) [IQR] | 52 (17.1–71.3) [38.1–60.2] | 53.2 (19–70.9) [42.9–62.3] | 0.3 |
| Time from diagnosis to transplant (months) median (range) [IQR] | 5 (1–71) [3–8] | 4 (1–61) [3–6] | 0.05 |
| Number of CD34 + cells infused (E + 06) median (range) [IQR] | 5.9 (0.9–10.7) [4.5–7.2] | 5.5 (0.6–10.2) [4.2–6.7] | 0.1 |
| Sex mismatch | 0.012 | ||
| Female to male | 27 (18%) | 43 (30%) | |
| Other combination | 123 (82%) | 98 (70%) | |
| Diagnosis | 0.058 | ||
| Acute leukemia | 93 (61%) | 107 (74%) | |
| Lymphoma | 19 (12%) | 12 (8%) | |
| MDS | 41 (27%) | 26 (18%) | |
| Disease status | 0.2 | ||
| CR | 94 (64%) | 98 (70%) | |
| Not in CR | 54 (36%) | 42 (30%) | |
| ATG | 0.5 | ||
| No | 77 (50%) | 79 (54%) | |
| Yes | 76 (50%) | 66 (46%) | |
| Conditioning intensity | 0.9 | ||
| MAC/CHEMO | 30 (20%) | 32 (22%) | |
| MAC/TBI | 26 (17%) | 25 (17%) | |
| RIC | 95 (63%) | 87 (61%) | |
| Karnovsky Score | 0.8 | ||
| < = 80 | 23 (16%) | 21 (15%) | |
| 90–100 | 125 (85%) | 122 (85%) | |
| Missing | 5 | 2 | |
| Disease risk index | 0.8 | ||
| Low | 6 (4%) | 4 (3%) | |
| Intermediate | 86 (59%) | 88 (65%) | |
| High | 48 (33%) | 39 (29%) | |
| Very high | 5 (3%) | 5 (4%) | |
| Missing | 8 | 9 |