TABLE 3.
Relative expression levels of 23 genes affected by SoxR G121P in response to doxycycline
| Gene | Name of gene product | Fold change in expression determined by: |
|
|---|---|---|---|
| RNA-seq | Real-time qPCR | ||
| rpsR | 30S ribosomal subunit protein S18 | −25.93 | −166.96 |
| rplD | 50S ribosomal subunit protein L4 | −20.44 | −85.04 |
| rpsF | 30S ribosomal subunit protein S6 | −18.45 | −156.14 |
| rpsC | 30S ribosomal subunit protein S3 | −16.13 | −9.04 |
| rpsQ | 30S ribosomal subunit protein S17 | −8.16 | −83.87 |
| rpsB | 30S ribosomal subunit protein S2 | −6.59 | −60.13 |
| rplE | 50S ribosomal subunit protein L5 | −3.90 | −23.53 |
| fbaB | Fructose-bisphosphate aldolase class I | 106.86 | 15.60 |
| pgi | Phosphohexose isomerase | 10.24 | 1.24 |
| pfkA | 6-Phosphofructokinase I | −44.20 | −2,586.29 |
| aceE | Pyruvate dehydrogenase | −3.82 | −20.16 |
| talA | Transaldolase A | 80.72 | 13.06 |
| tktB | Transketolase B | 60.17 | 11.82 |
| fumC | Fumarate hydratase | 76.81 | 7.52 |
| sucD | Succinyl-CoA synthetase | 17.50 | 1.75 |
| acnA | Aconitate hydratase | 17.49 | 2.44 |
| sucA | 2-Oxoglutarate decarboxylase | 14.18 | 1.69 |
| mqo | Malate dehydrogenase | −15.55 | −7.78 |
| aceA | Isocitrate lyase | 13.08 | 1.47 |
| aceB | Malate synthase A | 12.00 | 1.53 |
| ndh | NADH dehydrogenase II | −3.66 | −4.82 |
| gadB | Glutamate decarboxylase | 873.93 | 33.98 |
| gadA | Glutamate decarboxylase | 355.04 | 8.22 |