Table 3.

Univariate and multivariate analysis of clinical factors associated with Recurrence-Free Survival among patients with ESCC.

Variates	Univariate analysis			Multivariate analysis
	HR (95%CI)	χ2	p	HR (95%CI)	χ2	p
Gender	0.694(0.559–0.862)	10.870	0.001	0.717 (0.573–0.898)	8.444	0.004
Age	1.032 (0.857–1.243)	0.112	0.738
Location	1.258 (1.104–1.433)	11.925	0.001		3.536	0.316
Cervical				Reference
Upper thoracic				1.171 (0.750–1.830)	0.482	0.488
Middle thoracic				1.331 (0.880–2.013)	1.832	0.176
Lower thoracic				1.474 (0.919–2.364)	2.597	0.107
T stage	1.479 (1.320–1.657)	45.647	0.000		27.225	0.000
T4				Reference
T1				0.386 (0.166–0.897)	4.890	0.027
T2				0.595 (0.462–0.765)	16.269	0.000
T3				0.563 (0.437–0.724)	20.028	0.000
N stage	1.799 (1.408–2.299)	22.011	0.000	1.449 (1.116–1.881)	7.755	0.005
RT dose	1.063 (0.883–1.280)	0.414	0.520
Treatment	0.749 (0.622–0.901)	9.346	0.002	0.628 (0.518–0.762)	22.314	0.000
LDH	1.280 (1.060–1.546)	6.589	0.010	1.304 (1.076–1.580)	7.317	0.007
Neutrophils	1.427 (1.182–1.723)	13.668	0.000	1.242 (1.013–1.522)	4.352	0.037
NLR	1.389 (1.142–1.688)	10.873	0.001	1.021 (0.825–1.264)	0.037	0.848