Table 4.

Univariate and multivariate analysis of clinical factors associated with Overall Survival among patients with ESCC.

Variates	Univariate analysis			Multivariate analysis
	HR (95%CI)	χ2	p	HR (95%CI)	χ2	p
Gender	0.695 (0.558–0.866)	10.536	0.001	0.727 (0.580–0.911)	7.648	0.006
Age	1.048 (0.868–1.265)	0.239	0.625
LocationCervical	1.274 (1.116–1.454)	12.887	0.000	Reference	3.534	0.316
Upper thoracic				1.154 (0.733–1.819)	0.383	0.536
Middle thoracic				1.319 (0.865–2.011)	1.650	0.199
Lower thoracic				1.471 (0.910–2.379)	2.481	0.115
T stage	1.525 (1.358–1.713)	50.716	0.000		32.151	0.000
T4				Reference
T1				0.367 (0.158–0.852)	5.443	0.020
T2				0.568 (0.439–0.735)	18.490	0.000
T3				0.527 (0.408–0.680)	24.268	0.000
N stage	1.799 (1.389–2.280)	20.741	0.000	1.430 (1.099–1.861)	7.077	0.008
RT dose	1.052 (0.871–1.270)	0.274	0.601
Treatment	0.758 (0.628–0.914)	8.360	0.004	0.638 (0.524–0.776)	20.177	0.000
LDH	1.265 (1.044–1.531)	5.772	0.016	1.283 (1.076–1.580)	6.278	0.012
Neutrophils	1.462 (1.208–1.771)	15.158	0.000	1.245 (1.012–1.532)	4.308	0.038
NLR	1.426 (1.171–1.738)	12.439	0.000	1.014 (0.8175–1.259)	0.016	0.899