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. 2020 Apr 15;11:270. doi: 10.3389/fpsyt.2020.00270

Table 4.

Overall incidence of suicidal drug overdose (per 10,000 person-years) and estimated hazard ratio according to copd patients with or without depression through the cox method.

Comparison cohort Total COPD COPD without depression COPD with depression
Variable (N=109,040) (N=54,520) (N=48,879) (N=5,641)
Person-years
 Event, n 1835 2741 2265 476
 Rate# 6.11 23.8 20.9 71.2
Crude HR (95% CI) 1(Reference) 3.83(3.61, 4.07)*** 3.36(3.16, 3.58)*** 11.5(10.4, 12.7)***
Adjusted HR$ (95% CI) 1(Reference) 3.59(3.37, 3.81)*** 3.24(3.04, 3.45)*** 10.0(8.99, 11.2)***
Crude HR (95% CI) 1(Reference) 3.42(3.10, 3.78)***
Adjusted HR$ (95% CI) 1(Reference) 3.09(2.77, 3.4)***

#Incidence rate per 10,000 person-years. $Multivariable analysis included age, monthly income, urbanization level, and comorbidities of schizophrenia, alcohol-related illness, anxiety, mental disorders, insomnia, diabetes mellitus, hypertension, hyperlipidemia, chronic obstructive pulmonary disease, coronary artery disease, stroke, and cirrhosis. ***P < .001.